Custom Synthesis
The custom synthesis of commercially difficult to obtain, fine organic compounds for use as pharmaceutical analytical reference standards, for screening programmes, or as synthetic intermediates can be undertaken.
EPP Ltd’s team of qualified and highly experienced organic synthetic chemists are specialists in the field of custom synthesis. The custom synthesis (typical scale 100mg – 100g) and full analysis / certification of unique or “hard-to find” organic chemicals for QC and GxP analytical applications for the pharmaceutical industry is facilitated at our custom built facility.
We specialise in synthesising :-
* impurity reference standards* internal reference standards
* metabolites
* stable labelled compounds
* degradation compounds
Re-certification of analytical reference standards (where the expiry date has been reached) can also be conducted to extend shelf-life.
EPP Ltd's custom synthesis service incorporates the following features:
* Rapid and cost-effective response to client queries.
* Highly qualified staff have an in-depth knowledge and practical expertise in organic chemistry.
* Perform custom synthesis to an agreed product specification. Ability to work on a wide range of scales from millimolar to molar.
* Capabilities to carry out impurity isolation and identification.
Over the last 17 years we have accumulated vast experience in the custom synthesis of various types of certified analytical reference standards on a scale ranging from milligrams [for initial identification purposes] to kilograms [for toxicity, process validation and environmental fate studies], and at a purity ranging from 95-100%.